Air pollution is the leading risk factor among all risks in the global burden of diseases. Our research utilizes time-series and case-crossover designs to assess the adverse health effects of short-term exposure to air pollutants and their interactions with extreme temperatures from a local to global scale. Our recent work sheds light on the effect of ambient ultrafine particles on nonfatal heart attacks, the link between ambient particulate matter pollution and increased mental health outpatient visits, and the adverse mortality effects of ambient carbon monoxide at levels well below the current air quality guidelines. Our ongoing and future work will further address the health effects of both short-term and long-term exposure to ambient air pollution and the interactive effects of combined exposure to air pollution and extreme weather events.
Cardiovascular effects of short-term exposure to ambient particulate air pollution
This study shows that transient (6-12 hours) exposure to particle number, length, and surface area concentrations or other potentially related exposures may trigger the onset of nonfatal myocardial infraction.
Chen, et al. Environmental Health Perspectives, 2020
Mental health effects of ambient air pollution
This study shows more ambient particulate matter pollution could be linked to higher rates of mental health service utilization.
Lowe, et al. Environ Res, 2020.
Long-term ozone exposure and cognitive impairment
In this nationwide prospective cohort study of Chinese older adults aged 65–110 years, long-term exposure to ozone was associated with an elevated risk of cognitive impairment after controlling for potential confounders. The exposure-response curve showed a continuously elevated cognitive impairment risk with increasing ozone concentrations.
Qi et al. Environment International, 2022
Even “safe” ambient CO levels may harm health
In collaboration with the Multi-Country Multi-City (MCC) Collaborative Research Network, using data collected from 337 cities across 18 countries from 1979 to 2016, we found that even short-term exposure to ambient carbon monoxide (CO) — at levels below the current air quality guidelines and considered safe — had an association with increased mortality.
Chen et al. The Lancet Planetary Health, 2021.
Short-term exposure to ambient particulate matter pollution and emergency room for urinary system disease
In this study, we found that short-term exposures to PM2.5 and PM10 are risk factors for urinary system disease (UD), based on daily UD inpatient hospital admissions through the emergency room (ER-admissions) in Beijing during 2013–2018.
Chu et al. Environmental Pollution, 2021
Interactive health effects of air pollution and temperature
This study reveals that high temperature could enhance the harmful effects of air pollution and high air pollution could also modify heat effects on mortality.